Research Progress on the Gut-Muscle Axis in Sarcopenia
DOI:
https://doi.org/10.62836/amr.v4i1.543Keywords:
gut microbiota, skeletal muscle atrophy, gut muscle axis, metabolic factors, nutritional interventionsAbstract
In recent years, the gut muscle axis has become an important direction for studying skeletal muscle atrophy. With a deeper understanding of the gut microbiota, an increasing number of studies have shown a close relationship between gut health and skeletal muscle function. Skeletal muscle atrophy is an important issue affecting the health of the elderly population, and its pathogenesis is complex, involving multiple aspects such as metabolic factors, inflammatory reactions, and nutritional status. However, despite the increasing number of related studies, the specific mechanisms by which gut microbiota affects skeletal muscle health are still not clear enough. This review aims to explore the relationship between gut microbiota and skeletal muscle health, analyze its potential mechanisms and clinical significance. The article first introduces the basic concept of the gut muscle axis and recent research progress, then delves into its influencing factors in skeletal muscle atrophy, summarizes the latest research results, and finally proposes future research directions and possible clinical applications, in order to provide reference for further research in this field.
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Copyright (c) 2025 Jiye Liu, Jiachun Li, Qian Sun, Shengli Huang, Shuang Shen
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This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommerical-NoDerivatives 4.0 International License.
